CTGF Increases IL-6 Expression in Human Synovial Fibroblasts through Integrin-Dependent Signaling Pathway

BACKGROUND: Connective tissue growth factor (CTGF; also known as CCN2) is an inflammatory mediator, and shows elevated levels in regions of severe injury and inflammatory diseases. CTGF is abundantly expressed in osteoarthritis (OA). However, the relationship between CTGF and IL-6 in OA synovial fib...

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Bibliographische Detailangaben
Hauptverfasser: Liu, Shan-Chi, Hsu, Chin-Jung, Chen, Hsien-Te, Tsou, Hsi-Kai, Chuang, Show-Mei, Tang, Chih-Hsin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515445/
https://ncbi.nlm.nih.gov/pubmed/23227240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0051097
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