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Cloning, expression, purification, crystallization and preliminary X-ray crystallographic analyses of threonyl-tRNA synthetase editing domain from Aeropyrum pernix

The proofreading function of aminoacyl-tRNA synthetases is crucial in maintaining the fidelity of protein synthesis. Most archaeal threonyl-tRNA synthetases (ThrRSs) possess a unique proofreading domain unrelated to their eukaryotic/bacterial counterpart. The crystal structure of this domain from th...

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Библиографические подробности
Главные авторы: Ahmad, Sadeem, Sravankumar, Antony S. K., Kruparani, Shobha P., Sankaranarayanan, Rajan
Формат: Artigo
Язык:Inglês
Опубликовано: International Union of Crystallography 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515388/
https://ncbi.nlm.nih.gov/pubmed/23143256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112042066
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