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Purification, crystallization and preliminary X-ray diffraction analysis of an acidic phospholipase A(2) with vasoconstrictor activity from Agkistrodon halys pallas venom

Phospholipases A(2) (PLA(2)s) are the major component of snake venoms and exert a variety of relevant toxic actions such as neurotoxicity and myotoxicity, amongst others. An acidic PLA(2), here named AhV_aPA, was purified from Agkistrodon halys pallas venom by means of a three-step chromatographic p...

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Détails bibliographiques
Auteurs principaux: Zou, Zhisong, Zeng, Fuxing, Zhang, Lu, Niu, Liwen, Teng, Maikun, Li, Xu
Format: Artigo
Langue:Inglês
Publié: International Union of Crystallography 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515374/
https://ncbi.nlm.nih.gov/pubmed/23143242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112038523
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