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Purification, crystallization and preliminary X-ray diffraction analysis of saxthrombin, a thrombin-like enzyme from Gloydius saxatilis venom

The snake-venom thrombin-like enzymes (SVTLEs) are a class of serine proteinases that show fibrinogen-clotting and esterolytic activities. Most TLEs convert fibrinogen to fibrin by releasing either fibrinopeptide A or fibrinopeptide B and cannot activate factor XIII. The enzymes hydrolyze fibrinogen...

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Detalhes bibliográficos
Main Authors: Wei, Wenqing, Zhao, Wei, Wang, Xiaoping, Teng, Maikun, Niu, Liwen
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2335164/
https://ncbi.nlm.nih.gov/pubmed/17671373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309107031429
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