Expression, purification, crystallization and preliminary X-ray diffraction analysis of human phosphoribosyl pyrophosphate synthetase 1 (PRS1)

Phosphoribosyl pyrophosphate synthetase (PRS; EC 2.7.6.1) catalyzes the reaction of ribose-5-phosphate (R5P) with ATP to yield AMP and PRPP (5-­phosphoribosyl-1-pyrophosphate), which is necessary for the de novo and salvage pathways of purine-, pyrimidine- and pyridine-nucleotide biosynthesis. PRPP...

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Detalhes bibliográficos
Main Authors: Tang, Wenying, Li, Xiaowu, Zhu, Zhiqiang, Tong, Shuilong, Li, Xu, Zhang, Xiao, Teng, Maikun, Niu, Liwen
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2006
Assuntos:
Crystallization Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2219982/
https://ncbi.nlm.nih.gov/pubmed/16682768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309106009067
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