Structure of the recombinant BPTI/Kunitz-type inhibitor rShPI-1A from the marine invertebrate Stichodactyla helianthus

The BPTI/Kunitz-type inhibitor family includes several extremely potent serine protease inhibitors. To date, the inhibitory mechanisms have only been studied for mammalian inhibitors. Here, the first crystal structure of a BPTI/Kunitz-type inhibitor from a marine invertebrate (rShPI-1A) is reported...

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Detalhes bibliográficos
Main Authors: García-Fernández, Rossana, Pons, Tirso, Meyer, Arne, Perbandt, Markus, González-González, Yamile, Gil, Dayrom, de los Angeles Chávez, María, Betzel, Christian, Redecke, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Structural Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515366/
https://ncbi.nlm.nih.gov/pubmed/23143234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112039085
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