Characterization of the temperature sensitive phenotype of the A/Ann Arbor/6/60 cold-adapted virus and its recombinants.

The A/Ann Arbor/6/60 cold-adapted (ca) donor virus had a 38 degrees C shutoff temperature when tested in MDCK tissue culture. ca recombinant viruses bearing all six "internal genes" of the A/Ann Arbor/6/60 ca donor virus and the surface antigens of wild-type virus can manifest a 1,000-fold...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Murphy, B R, Maassab, H F, Wood, F T, Chanock, R M
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1981
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC351536/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7251154/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.32.2.960-963.1981
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