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Four viral genes independently contribute to attenuation of live influenza A/Ann Arbor/6/60 (H2N2) cold-adapted reassortant virus vaccines.

Clinical studies previously demonstrated that live influenza A virus vaccines derived by genetic reassortment from the mating of influenza A/Ann Arbor/6/60 (H2N2) cold-adapted (ca) donor virus with epidemic wild-type influenza A viruses are reproducibly safe, infectious, immunogenic, and efficacious...

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Bibliografiska uppgifter
Huvudupphovsmän: Snyder, M H, Betts, R F, DeBorde, D, Tierney, E L, Clements, M L, Herrington, D, Sears, S D, Dolin, R, Maassab, H F, Murphy, B R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1988
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC250559/
https://ncbi.nlm.nih.gov/pubmed/3336068
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