Dysregulation of miR-31 and miR-21 induced by zinc deficiency promotes esophageal cancer

Zinc deficiency (ZD) increases the risk of esophageal squamous cell carcinoma (ESCC). In a rat model, chronic ZD induces an inflammatory gene signature that fuels ESCC development. microRNAs regulate gene expression and are aberrantly expressed in cancers. Here we investigated whether chronic ZD (23...

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Autors principals: Alder, Hansjuerg, Taccioli, Cristian, Chen, Hongping, Jiang, Yubao, Smalley, Karl J, Fadda, Paolo, Ozer, Hatice G, Huebner, Kay, Farber, John L, Croce, Carlo M, Fong, Louise Y.Y
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514898/
https://ncbi.nlm.nih.gov/pubmed/22689922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs204
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