Repression of Esophageal Neoplasia and Inflammatory Signaling by Anti-miR-31 Delivery In Vivo

BACKGROUND: Overexpression of microRNA-31 (miR-31) is implicated in the pathogenesis of esophageal squamous cell carcinoma (ESCC), a deadly disease associated with dietary zinc deficiency. Using a rat model that recapitulates features of human ESCC, the mechanism whereby Zn regulates miR-31 expressi...

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Veröffentlicht in:J Natl Cancer Inst
Hauptverfasser: Taccioli, Cristian, Garofalo, Michela, Chen, Hongping, Jiang, Yubao, Tagliazucchi, Guidantonio Malagoli, Di Leva, Gianpiero, Alder, Hansjuerg, Fadda, Paolo, Middleton, Justin, Smalley, Karl J., Selmi, Tommaso, Naidu, Srivatsava, Farber, John L., Croce, Carlo M., Fong, Louise Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675101/
https://ncbi.nlm.nih.gov/pubmed/26286729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv220
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