MicroRNA dysregulation and esophageal cancer development depend on the extent of zinc dietary deficiency

Zinc deficiency (ZD) increases the risk of esophageal squamous cell carcinoma (ESCC), and marginal ZD is prevalent in humans. In rats, marked-ZD (3 mg Zn/kg diet) induces a proliferative esophagus with a 5-microRNA signature (miR-31, -223, -21, -146b, -146a) and promotes ESCC. Here we report that mo...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Fong, Louise Y., Taccioli, Cristian, Jing, Ruiyan, Smalley, Karl J., Alder, Hansjuerg, Jiang, Yubao, Fadda, Paolo, Farber, John L., Croce, Carlo M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Priority Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905434/
https://ncbi.nlm.nih.gov/pubmed/26918602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7561
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