Accelerated elimination of ultraviolet-induced DNA damage through apoptosis in CDC25A-deficient skin

Cell division cycle 25A (CDC25A) is a dual-specificity phosphatase that removes inhibitory phosphates from cyclin-dependent kinases, allowing cell-cycle progression. Activation of cell-cycle checkpoints following DNA damage results in the degradation of CDC25A, leading to cell-cycle arrest. Ultravio...

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Detalhes bibliográficos
Main Authors: Yanagida, Jodi, Hammiller, Brianna, Al-Matouq, Jenan, Behrens, Michaela, Trempus, Carol S., Repertinger, Susan K., Hansen, Laura A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514895/
https://ncbi.nlm.nih.gov/pubmed/22764135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgs168
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