Targeting 14-3-3ε-CDC25A interactions to trigger apoptotic cell death in skin cancer

Non-melanoma skin cancer is the most common form of cancer worldwide. We previously documented an anti-apoptotic role for CDC25A in cutaneous squamous cell carcinoma (SCC), an activity dependent on its association with 14-3-3 proteins. We hypothesized that targeting CDC25A-14-3-3ε interactions may b...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Holmes, Thomas R., Al-Matouq, Jenan, Holmes, Matti, Nicola, Lauren, Rudd, Justin C., Lovas, Sándor, Hansen, Laura A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476737/
https://ncbi.nlm.nih.gov/pubmed/32934772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27700
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