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Permeant calcium ion feed-through regulation of single inositol 1,4,5-trisphosphate receptor channel gating

The ubiquitous inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) Ca(2+) release channel plays a central role in the generation and modulation of intracellular Ca(2+) signals, and is intricately regulated by multiple mechanisms including cytoplasmic ligand (InsP(3), free Ca(2+), free ATP(4−)...

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Main Authors: Vais, Horia, Foskett, J. Kevin, Ullah, Ghanim, Pearson, John E., Daniel Mak, Don-On
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514735/
https://ncbi.nlm.nih.gov/pubmed/23148262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201210804
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