Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC

The microRNA (miRNA)-induced silencing complex (miRISC) controls gene expression by a posttranscriptional mechanism involving translational repression and/or promoting messenger RNA (mRNA) deadenylation and degradation. The GW182/TNRC6 (GW) family proteins are core components of the miRISC and are e...

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Detalhes bibliográficos
Main Authors: Castilla-Llorente, Virginia, Spraggon, Lee, Okamura, Miwako, Naseeruddin, Saif, Adamow, Matthew, Qamar, Sarah, Liu, Jidong
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3514032/
https://ncbi.nlm.nih.gov/pubmed/22891262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201201153
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