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The importance of serine 776 in Ataxin-1 partner selection: A FRET Analysis
Anomalous expansion of a polymorphic tract in Ataxin-1 causes the autosomal dominant spinocerebellar ataxia type 1. In addition to polyglutamine expansion, requirements for development of pathology are phosphorylation of serine 776 in Ataxin-1 and nuclear localization of the protein. The phosphoryla...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3513968/ https://ncbi.nlm.nih.gov/pubmed/23213356 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00919 |
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