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Kaleidoscopic protein–protein interactions in the life and death of ataxin-1: new strategies against protein aggregation()
Understanding how proteins protect themselves from aberrant aggregation is of primary interest for understanding basic biology, protein biochemistry, and human disease. We discuss the paradigmatic example of ataxin-1 (Atx1), the protein responsible for neurodegenerative spinocerebellar ataxia type 1...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Applied Science Publishing
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3988977/ https://ncbi.nlm.nih.gov/pubmed/24636457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2014.02.003 |
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