The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

In the mucosa, the immune pathways discriminating between colonizing and invasive Candida, thus inducing tolerance or inflammation, are poorly understood. Th17 responses induced by Candida albicans hyphae are central for the activation of mucosal antifungal immunity. An essential step for the discri...

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Detalhes bibliográficos
Main Authors: Cheng, Shih-Chin, van de Veerdonk, Frank L., Lenardon, Megan, Stoffels, Monique, Plantinga, Theo, Smeekens, Sanne, Rizzetto, Lisa, Mukaremera, Liliane, Preechasuth, Kanya, Cavalieri, Duccio, Kanneganti, Thirumala Devi, van der Meer, Jos W. M., Kullberg, Bart Jan, Joosten, Leo A. B., Gow, Neil A. R., Netea, Mihai G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2011
Assuntos:
Host Defense & Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513931/
https://ncbi.nlm.nih.gov/pubmed/21531876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1210702
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