The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

In the mucosa, the immune pathways discriminating between colonizing and invasive Candida, thus inducing tolerance or inflammation, are poorly understood. Th17 responses induced by Candida albicans hyphae are central for the activation of mucosal antifungal immunity. An essential step for the discri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cheng, Shih-Chin, van de Veerdonk, Frank L., Lenardon, Megan, Stoffels, Monique, Plantinga, Theo, Smeekens, Sanne, Rizzetto, Lisa, Mukaremera, Liliane, Preechasuth, Kanya, Cavalieri, Duccio, Kanneganti, Thirumala Devi, van der Meer, Jos W. M., Kullberg, Bart Jan, Joosten, Leo A. B., Gow, Neil A. R., Netea, Mihai G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Leukocyte Biology 2011
Schlagworte:
Host Defense & Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513931/
https://ncbi.nlm.nih.gov/pubmed/21531876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1210702
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