Protein kinase inhibitors that inhibit induction of lytic program and replication of Epstein-Barr Virus

Signaling pathways mediating Epstein-Barr virus (EBV) reactivation by Ag-bound B-cell receptor (BCR) were analyzed using a panel of 80 protein kinase inhibitors. Broad range protein kinase inhibitors Staurosporin, K252A, and PKC-412 significantly reduced the EBV genome copy numbers measured 48 hours...

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Main Authors: Goswami, R., Gershburg, S., Satorius, A., Gershburg, E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513622/
https://ncbi.nlm.nih.gov/pubmed/23058855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2012.09.021
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