The Dermatan Sulfate Proteoglycan Decorin Modulates α2β1 Integrin and the Vimentin Intermediate Filament System during Collagen Synthesis

Decorin, a small leucine-rich proteoglycan harboring a dermatan sulfate chain at its N-terminus, is involved in regulating matrix organization and cell signaling. Loss of the dermatan sulfate of decorin leads to an Ehlers-Danlos syndrome characterized by delayed wound healing. Decorin-null (Dcn(−/−)...

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Main Authors: Jungmann, Oliver, Nikolovska, Katerina, Stock, Christian, Schulz, Jan-Niklas, Eckes, Beate, Riethmüller, Christoph, Owens, Rick T., Iozzo, Renato V., Seidler, Daniela G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513320/
https://ncbi.nlm.nih.gov/pubmed/23226541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050809
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