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A decorin-deficient matrix affects skin chondroitin/dermatan sulfate levels and keratinocyte function
Decorin is a small leucine-rich proteoglycan harboring a single glycosaminoglycan chain, which, in skin, is mainly composed of dermatan sulfate (DS). Mutant mice with targeted disruption of the decorin gene (Dcn(−/−)) exhibit an abnormal collagen architecture in the dermis and reduced tensile streng...
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| Publicado no: | Matrix Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5165699/ https://ncbi.nlm.nih.gov/pubmed/24447999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2014.01.003 |
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