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Decorin is an autophagy-inducible proteoglycan and is required for proper in vivo autophagy

We have recently discovered that soluble extracellular matrix constituents regulate autophagy via an outside-in signaling pathway. Decorin, a secreted proteoglycan, evokes autophagy in endothelial cells and mitophagy in breast carcinoma cells. However, it is not known whether decorin expression can...

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Bibliographic Details
Published in:Matrix Biol
Main Authors: Gubbiotti, Maria A., Neill, Thomas, Frey, Helena, Schaefer, Liliana, Iozzo, Renato V.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4661125/
https://ncbi.nlm.nih.gov/pubmed/26344480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2015.09.001
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