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TGFβ in Cancer

The transforming growth factor β (TGFβ) signaling pathway is a key player in metazoan biology, and its misregulation can result in tumor development. The regulatory cytokine TGFβ exerts tumor-suppressive effects that cancer cells must elude for malignant evolution. Yet, paradoxically, TGFβ also modu...

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Bibliographic Details
Main Author: Massagué, Joan
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512574/
https://ncbi.nlm.nih.gov/pubmed/18662538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.07.001
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