Phosphatidylinositol 4-kinase IIα function at endosomes is regulated by the ubiquitin ligase Itch

Phosphatidylinositol (PI) 4-phosphate (PI(4)P) and its metabolizing enzymes serve important functions in cell signalling and membrane traffic. PI 4-kinase type IIα (PI4KIIα) regulates Wnt signalling, endosomal sorting of signalling receptors, and promotes adaptor protein recruitment to endosomes and...

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Hlavní autoři: Mössinger, Julia, Wieffer, Marnix, Krause, Eberhard, Freund, Christian, Gerth, Fabian, Krauss, Michael, Haucke, Volker
Médium: Artigo
Jazyk:Inglês
Vydáno: European Molecular Biology Organization 2012
Témata:
Scientific Reports
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512407/
https://ncbi.nlm.nih.gov/pubmed/23146885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.164
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