ATM kinase activity modulates ITCH E3-ubiquitin ligase activity

Ataxia Telangiectasia Mutated (ATM) kinase, a central regulator of the DNA damage response regulates the activity of several E3-ubiquitin ligases and the ubiquitination-proteasome system is a consistent target of ATM. ITCH is an E3-ubiquitin ligase that modulates the ubiquitination of several target...

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Bibliographische Detailangaben
Hauptverfasser: Santini, Simonetta, Stagni, Venturina, Giambruno, Roberto, Fianco, Giulia, Di Benedetto, Anna, Mottolese, Marcella, Pellegrini, Manuela, Barilà, Daniela
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938399/
https://ncbi.nlm.nih.gov/pubmed/23435430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.52
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