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ATM kinase activity modulates ITCH E3-ubiquitin ligase activity
Ataxia Telangiectasia Mutated (ATM) kinase, a central regulator of the DNA damage response regulates the activity of several E3-ubiquitin ligases and the ubiquitination-proteasome system is a consistent target of ATM. ITCH is an E3-ubiquitin ligase that modulates the ubiquitination of several target...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3938399/ https://ncbi.nlm.nih.gov/pubmed/23435430 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.52 |
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