Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation

Overexpression of ERBB2 or ERBB3 is associated with cancer development and poor prognosis. In this study, we show that reactive oxygen species (ROS) induce both ERBB2 and ERBB3 expression in vitro and in vivo. We also identify that miR-199a and miR-125b target ERBB2 and/or ERBB3 in ovarian cancer ce...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: He, Jun, Xu, Qing, Jing, Yi, Agani, Faton, Qian, Xu, Carpenter, Richard, Li, Qi, Wang, Xin-Ru, Peiper, Stephen S, Lu, Zhimin, Liu, Ling-Zhi, Jiang, Bing-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2012
Assuntos:
Scientific Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512405/
https://ncbi.nlm.nih.gov/pubmed/23146892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2012.162
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados