TNFα signals through specialized factories where responsive coding and miRNA genes are transcribed

Tumour necrosis factor alpha (TNFα) is a potent cytokine that signals through nuclear factor kappa B (NFκB) to activate a subset of human genes. It is usually assumed that this involves RNA polymerases transcribing responsive genes wherever they might be in the nucleus. Using primary human endotheli...

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Detalhes bibliográficos
Main Authors: Papantonis, Argyris, Kohro, Takahide, Baboo, Sabyasachi, Larkin, Joshua D, Deng, Binwei, Short, Patrick, Tsutsumi, Shuichi, Taylor, Stephen, Kanki, Yasuharu, Kobayashi, Mika, Li, Guoliang, Poh, Huay-Mei, Ruan, Xiaoan, Aburatani, Hiroyuki, Ruan, Yijun, Kodama, Tatsuhiko, Wada, Youichiro, Cook, Peter R
Formato: Artigo
Idioma:Inglês
Publicado em: European Molecular Biology Organization 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512387/
https://ncbi.nlm.nih.gov/pubmed/23103767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.288
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