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Active RNA Polymerases: Mobile or Immobile Molecular Machines?

It is widely assumed that active RNA polymerases track along their templates to produce a transcript. We test this using chromosome conformation capture and human genes switched on rapidly and synchronously by tumour necrosis factor alpha (TNFα); one is 221 kbp SAMD4A, which a polymerase takes more...

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Detalhes bibliográficos
Main Authors: Papantonis, Argyris, Larkin, Joshua D., Wada, Youichiro, Ohta, Yoshihiro, Ihara, Sigeo, Kodama, Tatsuhiko, Cook, Peter R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2903595/
https://ncbi.nlm.nih.gov/pubmed/20644712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1000419
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