Reciprocal expression of MRTF-A and myocardin is crucial for pathological vascular remodelling in mice

Myocardin-related transcription factor (MRTF)-A is a Rho signalling-responsive co-activator of serum response factor (SRF). Here, we show that induction of MRTF-A expression is key to pathological vascular remodelling. MRTF-A expression was significantly higher in the wire-injured femoral arteries o...

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Autors principals: Minami, Takeya, Kuwahara, Koichiro, Nakagawa, Yasuaki, Takaoka, Minoru, Kinoshita, Hideyuki, Nakao, Kazuhiro, Kuwabara, Yoshihiro, Yamada, Yuko, Yamada, Chinatsu, Shibata, Junko, Usami, Satoru, Yasuno, Shinji, Nishikimi, Toshio, Ueshima, Kenji, Sata, Masataka, Nakano, Hiroyasu, Seno, Takahiro, Kawahito, Yutaka, Sobue, Kenji, Kimura, Akinori, Nagai, Ryozo, Nakao, Kazuwa
Format: Artigo
Idioma:Inglês
Publicat: European Molecular Biology Organization 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512386/
https://ncbi.nlm.nih.gov/pubmed/23103763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2012.296
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