Antitumor T-cell responses contribute to the effects of dasatinib on c-KIT mutant murine mastocytoma and are potentiated by anti-OX40

Targeted and immune-based therapies are thought to eradicate cancer cells by different mechanisms, and these approaches could possibly complement each other when used in combination. In this study, we report that the in vivo antitumor effects of the c-KIT inhibitor, dasatinib, on the c-KIT mutant P8...

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Главные авторы: Yang, Yan, Liu, Chengwen, Peng, Weiyi, Lizée, Gregory, Overwijk, Willem W., Liu, Yang, Woodman, Scott E., Hwu, Patrick
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Hematology 2012
Предметы:
Immunobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512233/
https://ncbi.nlm.nih.gov/pubmed/22936666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-02-407163
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