Insertional Mutagenesis by a Hybrid PiggyBac and Sleeping Beauty Transposon in the Rat

A hybrid piggyBac/Sleeping Beauty transposon-based insertional mutagenesis system that can be mobilized by simple breeding was established in the rat. These transposons were engineered to include gene trap sequences and a tyrosinase (Tyr) pigmentation reporter to rescue the albinism of the genetic b...

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Detaylı Bibliyografya
Asıl Yazarlar: Furushima, Kenryo, Jang, Chuan-Wei, Chen, Diane W., Xiao, Ningna, Overbeek, Paul A., Behringer, Richard R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2012
Konular:
Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512136/
https://ncbi.nlm.nih.gov/pubmed/23023007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140855
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