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Insertional Mutagenesis by a Hybrid PiggyBac and Sleeping Beauty Transposon in the Rat
A hybrid piggyBac/Sleeping Beauty transposon-based insertional mutagenesis system that can be mobilized by simple breeding was established in the rat. These transposons were engineered to include gene trap sequences and a tyrosinase (Tyr) pigmentation reporter to rescue the albinism of the genetic b...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3512136/ https://ncbi.nlm.nih.gov/pubmed/23023007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.112.140855 |
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