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Force-Clamp Analysis Techniques Give Highest Rank to Stretched Exponential Unfolding Kinetics in Ubiquitin

Force-clamp spectroscopy reveals the unfolding and disulfide bond rupture times of single protein molecules as a function of the stretching force, point mutations, and solvent conditions. The statistics of these times reveal whether the protein domains are independent of one another, the mechanical...

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Detalhes bibliográficos
Main Authors: Lannon, Herbert, Vanden-Eijnden, Eric, Brujic, J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512049/
https://ncbi.nlm.nih.gov/pubmed/23200055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.10.022
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