Identification of an MRAP-Independent Melanocortin-2 Receptor: Functional Expression of the Cartilaginous Fish, Callorhinchus milii, Melanocortin-2 Receptor in CHO Cells

Phylogenetic analyses indicate that the genome of the cartilaginous fish, Callorhynchus milii (elephant shark), encodes a melanocortin-2 receptor (MC2R) ortholog. Expression of the elephant shark mc2r cDNA in Chinese hamster ovary (CHO) cells revealed that trafficking to the plasma membrane and func...

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Autors principals: Reinick, Christina L., Liang, Liang, Angleson, Joseph K., Dores, Robert M.
Format: Artigo
Idioma:Inglês
Publicat: Endocrine Society 2012
Matèries:
Glucocorticoids-CRH-ACTH-Adrenal
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3512025/
https://ncbi.nlm.nih.gov/pubmed/22919056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2012-1482
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