Flow-dependent regulation of Krüppel-like Factor 2 Is Mediated by MicroRNA-92a

BACKGROUND: Upregulated by atheroprotective flow, the transcription factor Krüppel-like factor 2 (KLF2) is crucial for maintaining endothelial function. MicroRNAs (miRNAs) are non-coding small RNAs that regulate gene expression at the post-transcriptional level. We examined the role of miRNAs, parti...

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Huvudupphovsmän: Wu, Wei, Xiao, Han, Laguna-Fernandez, Andrés, Villarreal, Guadalupe, Wang, Kuei-Chun, Geary, Greg G., Zhang, Yuzhi, Wang, Wei-Chi, Huang, Hsien-Da, Zhou, Jing, Li, Yi-Shuan, Chien, Shu, Garcia-Cardena, Guillermo, Shyy, John Y-J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511909/
https://ncbi.nlm.nih.gov/pubmed/21768538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.110.005108
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