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Flow Activation of AMP-Activated Protein Kinase in Vascular Endothelium Leads to Krüppel-Like Factor 2 Expression

OBJECTIVE: Vascular endothelial cells (ECs) confer atheroprotection at locations of the arterial tree where pulsatile laminar flow (PS) exists with a high shear stress and a large net forward direction. We investigated whether the PS-induced expression of the transcription factor Krüppel-Like Factor...

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Detalhes bibliográficos
Main Authors: Young, Angela, Wu, Wei, Sun, Wei, Larman, Harry B., Wang, Nanping, Li, Yi-Shuan, Shyy, John Y., Chien, Shu, García-Cardeña, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2766008/
https://ncbi.nlm.nih.gov/pubmed/19696400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.109.193540
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