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αvβ3-integrin is a major sensor and activator of innate immunity to herpes simplex virus-1
Pathogens are sensed by Toll-like receptors (TLRs) and a growing number of non-TLR receptors. Integrins constitute a family of signaling receptors exploited by viruses and bacteria to access cells. By gain- and loss-of-function approaches we found that αvβ3-integrin is a sensor of and plays a crucia...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3511702/ https://ncbi.nlm.nih.gov/pubmed/23150579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1212597109 |
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