Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells?

Field cancerization effects as well as isolated tumor cell foci extending well beyond the invasive tumor margin have been described previously to account for local recurrence rates following breast conserving surgery despite adequate surgical margins and breast radiotherapy. To look for evidence of...

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Opis bibliograficzny
Główni autorzy: Sadanandam, Anguraj, Lal, Aseem, Benz, Stephen C., Eppenberger-Castori, Serenella, Scott, Gary, Gray, Joe W., Spellman, Paul, Waldman, Fred, Benz, Christopher C.
Format: Artigo
Język:Inglês
Wydane: Springer US 2012
Hasła przedmiotowe:
Preclinical Study
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511697/
https://ncbi.nlm.nih.gov/pubmed/23104223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2290-3
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