Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells?

Field cancerization effects as well as isolated tumor cell foci extending well beyond the invasive tumor margin have been described previously to account for local recurrence rates following breast conserving surgery despite adequate surgical margins and breast radiotherapy. To look for evidence of...

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Bibliografski detalji
Glavni autori: Sadanandam, Anguraj, Lal, Aseem, Benz, Stephen C., Eppenberger-Castori, Serenella, Scott, Gary, Gray, Joe W., Spellman, Paul, Waldman, Fred, Benz, Christopher C.
Format: Artigo
Jezik:Inglês
Izdano: Springer US 2012
Teme:
Preclinical Study
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511697/
https://ncbi.nlm.nih.gov/pubmed/23104223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2290-3
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