Genomic aberrations in normal tissue adjacent to HER2-amplified breast cancers: field cancerization or contaminating tumor cells?

Field cancerization effects as well as isolated tumor cell foci extending well beyond the invasive tumor margin have been described previously to account for local recurrence rates following breast conserving surgery despite adequate surgical margins and breast radiotherapy. To look for evidence of...

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Detalhes bibliográficos
Main Authors: Sadanandam, Anguraj, Lal, Aseem, Benz, Stephen C., Eppenberger-Castori, Serenella, Scott, Gary, Gray, Joe W., Spellman, Paul, Waldman, Fred, Benz, Christopher C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2012
Assuntos:
Preclinical Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511697/
https://ncbi.nlm.nih.gov/pubmed/23104223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-2290-3
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