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Dual Delivery of Hepatocyte and Vascular Endothelial Growth Factors via a Protease-Degradable Hydrogel Improves Cardiac Function in Rats

Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most common cause of cardiac dysfunction due to local cell death and a temporally regulated inflammatory response. Current therapeutics are limited by delivery vehicles that do not address spatial and temporal aspects of...

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Détails bibliographiques
Auteurs principaux: Salimath, Apoorva S., Phelps, Edward A., Boopathy, Archana V., Che, Pao-lin, Brown, Milton, García, Andrés J., Davis, Michael E.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511447/
https://ncbi.nlm.nih.gov/pubmed/23226440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050980
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