Dual Delivery of Hepatocyte and Vascular Endothelial Growth Factors via a Protease-Degradable Hydrogel Improves Cardiac Function in Rats

Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most common cause of cardiac dysfunction due to local cell death and a temporally regulated inflammatory response. Current therapeutics are limited by delivery vehicles that do not address spatial and temporal aspects of...

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Detalhes bibliográficos
Main Authors: Salimath, Apoorva S., Phelps, Edward A., Boopathy, Archana V., Che, Pao-lin, Brown, Milton, García, Andrés J., Davis, Michael E.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511447/
https://ncbi.nlm.nih.gov/pubmed/23226440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050980
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