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Systemic Perturbation of the ERK Signaling Pathway by the Proteasome Inhibitor, MG132

Inhibition of the ubiquitin-proteasome protein degradation pathway has been identified as a viable strategy for anti-tumor therapy based on its broad effects on cell proliferation. By the same token, the variety of elicited effects confounds the interpretation of cell-based experiments using proteas...

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Autors principals: Cirit, Murat, Grant, Kyle G., Haugh, Jason M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511445/
https://ncbi.nlm.nih.gov/pubmed/23226437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050975
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