GDF5 Regulates TGFß-Dependent Angiogenesis in Breast Carcinoma MCF-7 Cells: In Vitro and In Vivo Control by Anti-TGFß Peptides

BACKGROUND: TGFß overproduction in cancer cells is one of the main characteristics of late tumor progression being implicated in metastasis, tumor growth, angiogenesis and immune response. We investigated the therapeutic efficacy of anti-TGFß peptides in the control of angiogenesis elicited by condi...

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Main Authors: Margheri, Francesca, Schiavone, Nicola, Papucci, Laura, Magnelli, Lucia, Serratì, Simona, Chillà, Anastasia, Laurenzana, Anna, Bianchini, Francesca, Calorini, Lido, Torre, Eugenio, Dotor, Javier, Feijoo, Esperanza, Fibbi, Gabriella, Del Rosso, Mario
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511424/
https://ncbi.nlm.nih.gov/pubmed/23226264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050342
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