Systemic Sclerosis-Endothelial Cell Antiangiogenic Pentraxin 3 and Matrix Metalloprotease 12 Control Human Breast Cancer Tumor Vascularization and Development in Mice

We have previously shown that endothelial cell matrix metalloprotease 12 (MMP12) and pentraxin 3 (PTX3) overproduction is the main alteration accounting for reduced proneness to angiogenesis in systemic sclerosis (SSc). On this basis, we stably transfected MMP12 and PTX3 in two breast cancer cell li...

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Detalhes bibliográficos
Main Authors: Margheri, Francesca, Serratì, Simona, Lapucci, Andrea, Anastasia, Chillà, Giusti, Betti, Pucci, Marco, Torre, Eugenio, Bianchini, Francesca, Calorini, Lido, Albini, Adriana, Ventura, Agostina, Fibbi, Gabriella, Del Rosso, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2745676/
https://ncbi.nlm.nih.gov/pubmed/19794969
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