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Encounter with antigen-specific primed CD4 T cells promotes MHC class II degradation in dendritic cells

Major histocompatibility complex class II molecules (MHC-II) on antigen presenting cells (APCs) engage the TCR on antigen-specific CD4 T cells, thereby providing the specificity required for T cell priming and the induction of an effective immune response. In this study, we have asked whether antige...

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Autors principals: Furuta, Kazuyuki, Ishido, Satoshi, Roche, Paul A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511074/
https://ncbi.nlm.nih.gov/pubmed/23129633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213868109
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