Dendritic Cell Activation Prevents MHC Class II Ubiquitination and Promotes MHC Class II Survival Regardless of the Activation Stimulus

The expression of MHC class II (MHC-II) on the surface of antigen-presenting cells, such as dendritic cells (DCs), is tightly regulated during cellular activation. Many cells, including DCs, are activated following stimulation of innate Toll-like receptors (TLRs) by products of microorganisms. In th...

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Bibliographic Details
Main Authors: Walseng, Even, Furuta, Kazuyuki, Goldszmid, Romina S., Weih, Karis A., Sher, Alan, Roche, Paul A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009902/
https://ncbi.nlm.nih.gov/pubmed/21047782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.157586
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