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Formation of triple-helical structures by the 3′-end sequences of MALAT1 and MENβ noncoding RNAs

Stability of the long noncoding-polyadenylated nuclear (PAN) RNA from Kaposi's sarcoma-associated herpesvirus is conferred by an expression and nuclear retention element (ENE). The ENE protects PAN RNA from a rapid deadenylation-dependent decay pathway via formation of a triple helix between th...

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Autores principales: Brown, Jessica A., Valenstein, Max L., Yario, Therese A., Tycowski, Kazimierz T., Steitz, Joan A.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511071/
https://ncbi.nlm.nih.gov/pubmed/23129630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217338109
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